Publications

Key publications

Guo Y, Li D, Zhang S, Yang Y, Liu JJ, Wang X, … Li D. (2018). Visualizing Intracellular Organelle and Cytoskeletal Interactions at Nanoscale Resolution on Millisecond Timescales. Cell, 175(5), 1430–42. https://doi.org/10.1016/j.cell.2018.09.057

Mortensen RD, Moore RP, Fogerson SM, Chiou HY, Obinero CV, Prabhu NK, … Kiehart DP. (2018). Identifying Genetic Players in Cell Sheet Morphogenesis Using a Drosophila Deficiency Screen for Genes on Chromosome 2R Involved in Dorsal Closure. G3 (Bethesda), 8(7), 2361–87. https://doi.org/10.1534/g3.118.200233

Kiehart DP, Crawford JM, Aristotelous A, Venakides S, & Edwards GS. (2017). Cell Sheet Morphogenesis: Dorsal Closure in Drosophila melanogaster as a Model System. Annu Rev Cell Dev Biol, 33, 169–202. https://doi.org/10.1146/annurev-cellbio-111315-125357

Lu H, Sokolow A, Kiehart DP, & Edwards GS. (2015). Remodeling Tissue Interfaces and the Thermodynamics of Zipping during Dorsal Closure in Drosophila. Biophys J, 109(11), 2406–17. https://doi.org/10.1016/j.bpj.2015.10.017

Chen BC, Legant WR, Wang K, Shao L, Milkie DE, Davidson MW, … Betzig E. (2014). Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution. Science, 346(6208):1257998(6208), 1257998. https://doi.org/10.1126/science.1257998

Wells AR, Zou RS, Tulu US, Sokolow AC, Crawford JM, Edwards GS, & Kiehart DP. (2014). Complete canthi removal reveals that forces from the amnioserosa alone are sufficient to drive dorsal closure in Drosophila. Mol Cell Biol, 25(22), 3552–6. https://doi.org/10.1091/mbc.E14-07-1190

Hunter GL, Crawford JM, Genkins JZ, & Kiehart DP. (2014). Ion channels contribute to the regulation of cell sheet forces during Drosophila dorsal closure. Development, 141(2), 325–34. https://doi.org/10.1242/dev.097097

Sokolow A, Toyama Y, Kiehart DP, & Edwards GS. (2012). Cell ingression and apical shape oscillations during dorsal closure in Drosophila. Biophys J, 102(5), 969–79. https://doi.org/10.1016/j.bpj.2012.01.027

Toyama Y, Peralta XG, Wells AR, Kiehart DP, & Edwards GS. (2008). Apoptotic force and tissue dynamics during Drosophila embryogenesis. Science, 321(5896), 1683–6. https://doi.org/10.1126/science.1157052

Peralta XG, Toyama Y, Kiehart DP, & Edwards GS. (2008). Emergent properties during dorsal closure in Drosophila morphogenesis. Phys Biol, 5(1), 1-11. https://doi.org/10.1088/1478-3975/5/1/015004

Franke JD, Montague RA, & Kiehart DP. (2005). Nonmuscle myosin II generates forces that transmit tension and drive contraction in multiple tissues during dorsal closure. Curr Biol, 15(24), 2208–21. https://doi.org/10.1016/j.cub.2005.11.064

Hutson MS, Tokutake Y, Chang MS, Bloor JW, Venakides S, Kiehart DP, & Edwards GS. (2003). Forces for morphogenesis investigated with laser microsurgery and quantitative modeling. Science, 300(5616), 145–9. https://doi.org/10.1126/science.1079552

Kiehart DP, Galbraith CG, Edwards KA, Rickoll WL, & Montague RA. (2000). Multiple forces contribute to cell sheet morphogenesis for dorsal closure in Drosophila. J Cell Biol, 149(2), 471–90. https://doi.org/10.1083/jcb.149.2.471

 

All publications

Fogerson SM, Mortensen RD, Moore RP, Chiou HY, Prabhu NK, Wei AH, Tsai D, Jadi O, Andoh-Baidoo K, Mudziviri M, Kiehart DP. (2020). Identifying Key Genetic Regions for Cell Sheet Morphogenesis on Chromosome 2L Using a Drosophila Deficiency Screen in Dorsal Closure. (Accepted for publication, G3).

Guo Y, Li D, Zhang S, Yang Y, Liu JJ, Wang X, … Li D. (2018). Visualizing Intracellular Organelle and Cytoskeletal Interactions at Nanoscale Resolution on Millisecond Timescales. Cell, 175(5), 1430–42. https://doi.org/10.1016/j.cell.2018.09.057

Kiehart DP, & Cooper JA. (2018). Contractile protein biochemistry in the Pollard Lab in Baltimore. Biophys Rev. Phys Rev E, 10(6), 1483–5. https://doi.org/10.1007/s12551-018-0477-5

Lo WC, Madrak C, Kiehart DP, & Edwards GS. (2018). Unified biophysical mechanism for cell-shape oscillations and cell ingression. Phys Rev E, 97(6–1), 062414. https://doi.org/10.1103/PhysRevE.97.062414

Aristotelous AC, Crawford JM, Edwards GS, Kiehart DP, & Venakides S. (2018). Mathematical models of dorsal closure. Prog Biophys Mol Biol, 137, 111–31. https://doi.org/10.1016/j.pbiomolbio.2018.05.009

Mortensen RD, Moore RP, Fogerson SM, Chiou HY, Obinero CV, Prabhu NK, … Kiehart DP. (2018). Identifying Genetic Players in Cell Sheet Morphogenesis Using a Drosophila Deficiency Screen for Genes on Chromosome 2R Involved in Dorsal Closure. G3 (Bethesda), 8(7), 2361–87. https://doi.org/10.1534/g3.118.200233

Kiehart DP, Crawford JM, Aristotelous A, Venakides S, & Edwards GS. (2017). Cell Sheet Morphogenesis: Dorsal Closure in Drosophila melanogaster as a Model System. Annu Rev Cell Dev Biol, 33, 169–202. https://doi.org/10.1146/annurev-cellbio-111315-125357

Cao J, Wang J, Jackman CP, Cox AH, Trembley MA, Balowski JJ, … Poss KD. (2017). Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue. Dev Cell, 42(6), 600–15. https://doi.org/10.1016/j.devcel.2017.08.024

Lu H, Sokolow A, Kiehart DP, & Edwards GS. (2016). Quantifying dorsal closure in three dimensions. Mol Cell Biol, 27(25), 3948–55. https://doi.org/10.1091/mbc.E16-06-0400

Marston DJ, Higgins CD, Peters KA, Cupp TD, Dickinson DJ, Pani AM, … Goldstein B. (2016). MRCK-1 Drives Apical Constriction in C. elegans by Linking Developmental Patterning to Force Generation. Curr Biol, 26(16), 2079–89. https://doi.org/10.1016/j.cub.2016.06.01

Lu H, Sokolow A, Kiehart DP, & Edwards GS. (2015). Remodeling Tissue Interfaces and the Thermodynamics of Zipping during Dorsal Closure in Drosophila. Biophys J, 109(11), 2406–17. https://doi.org/10.1016/j.bpj.2015.10.017

Goldstein B, & Kiehart DP. (2015). Moving Inward: Establishing the Mammalian Inner Cell Mass. Dev Cell, 34(4), 385–6. https://doi.org/10.1016/j.devcel.2015.08.007

Kiehart DP. (2015). Epithelial morphogenesis: apoptotic forces drive cell shape changes. Dev Cell, 32(5), 532–3. https://doi.org/10.1016/j.devcel.2015.02.020

Chen BC, Legant WR, Wang K, Shao L, Milkie DE, Davidson MW, … Betzig E. (2014). Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution. Science, 346(6208):1257998(6208), 1257998. https://doi.org/10.1126/science.1257998

Wells AR, Zou RS, Tulu US, Sokolow AC, Crawford JM, Edwards GS, & Kiehart DP. (2014). Complete canthi removal reveals that forces from the amnioserosa alone are sufficient to drive dorsal closure in Drosophila. Mol Cell Biol, 25(22), 3552–6. https://doi.org/10.1091/mbc.E14-07-1190

Hunter GL, Crawford JM, Genkins JZ, & Kiehart DP. (2014). Ion channels contribute to the regulation of cell sheet forces during Drosophila dorsal closure. Development, 141(2), 325–34. https://doi.org/10.1242/dev.097097

Sokolow A, Toyama Y, Kiehart DP, & Edwards GS. (2012). Cell ingression and apical shape oscillations during dorsal closure in Drosophila. Biophys J, 102(5), 969–79. https://doi.org/10.1016/j.bpj.2012.01.027

Roh-Johnson M, Shemer G, Higgins CD, McClellan JH, Werts AD, Tulu US, … Goldstein B. (2012). Triggering a cell shape change by exploiting preexisting actomyosin contractions. Science, 3356073(1232–5). https://doi.org/10.1126/science.1217869

Boyle MJ, French RL, Cosand KA, Dorman JB, Kiehart DP, & Berg CA. (2010). Division of labor: subsets of dorsal-appendage-forming cells control the shape of the entire tube. Dev Biol, 346(1), 68–79. https://doi.org/10.1016/j.ydbio.2010.07.018

Franke JD, Montague RA, & Kiehart DP. (2010). Nonmuscle myosin II is required for cell proliferation, cell sheet adhesion and wing hair morphology during wing morphogenesis. Dev Biol, 345(2), 117–32. https://doi.org/10.1016/j.ydbio.2010.06.028

Layton AT, Toyama Y, Yang GQ, Edwards GS, Kiehart DP, & Venakides S. (2009). Drosophila morphogenesis: tissue force laws and the modeling of dorsal closure. HFSP, 3(6), 441–60. https://doi.org/10.2976/1.3266062

Rodriguez-Diaz A, Toyama Y, Abravanel DL, Wiemann JM, Wells AR, Tulu US, … Kiehart DP. (2008). Actomyosin purse strings: renewable resources that make morphogenesis robust and resilient. HFSP, 2(4), 220–37. https://doi.org/10.2976/1.2955565

Toyama Y, Peralta XG, Wells AR, Kiehart DP, & Edwards GS. (2008). Apoptotic force and tissue dynamics during Drosophila embryogenesis. Science, 321(5896), 1683–6. https://doi.org/10.1126/science.1157052

Todi SV, Sivan-Loukianova E, Jacobs JS, Kiehart DP, & Eberl DF. (2008). Myosin VIIA, important for human auditory function, is necessary for Drosophila auditory organ development. PLoS One,  3(5), e2115. https://doi.org/10.1371/journal.pone.0002115

Peralta XG, Toyama Y, Kiehart DP, & Edwards GS. (2008). Emergent properties during dorsal closure in Drosophila morphogenesis. Phys Biol, 5(1), 1-11. https://doi.org/10.1088/1478-3975/5/1/015004

Franke JD, Montague RA, Rickoll WL, & Kiehart DP. (2007). An MYH9 human disease model in flies: site-directed mutagenesis of the Drosophila non-muscle myosin II results in hypomorphic alleles with dominant character. Hum Mol Genet, 16(24), 3160–73. https://doi.org/10.1093/hmg/ddm279

Peralta XG, Toyama Y, Hutson MS, Montague R, Venakides S, Kiehart DP, & Edwards GS. (2007). Upregulation of forces and morphogenic asymmetries in dorsal closure during Drosophila development. Biophys J, 92(7), 2583–96. https://doi.org/10.1529/biophysj.106.094110

Kiehart DP, Crawford JM, & Montague RA. (2007). Quantitative microinjection of Drosophila embryos: general strategy. CSH Protoc, Pdb.Top5https://doi.org/10.1101/pdb.top5

Kiehart DP, Crawford JM, & Montague RA. (2007). Quantitative microinjection of Drosophila embryos. CSH Protoc, Pdb.Prot4718. https://doi.org/10.1101/pdb.prot4718

Kiehart DP, Crawford JM, & Montague RA. (2007). Collection, dechorionation, and preparation of Drosophila embryos for quantitative microinjection. CSH Protoc, Pdb Prot4717https://doi.org/10.1101/pdb.prot4717

Franke JD, Boury AL, Gerald NJ, & Kiehart DP. (2006). Native nonmuscle myosin II stability and light chain binding in Drosophila melanogaster. Cell Motil Cytoskeleton, 63(10), 604–22. https://doi.org/10.1002/cm.20148

Yang Y, Kovács M, Sakamoto T, Zhang F, Kiehart DP, & Sellers JR. (2006). Dimerized Drosophila myosin VIIa: a processive motor. Proc Natl Acad Sci USA, 103(15), 5746–51. https://doi.org/10.1073/pnas.0509935103

Franke JD, Montague RA, & Kiehart DP. (2005). Nonmuscle myosin II generates forces that transmit tension and drive contraction in multiple tissues during dorsal closure. Curr Biol, 15(24), 2208–21. https://doi.org/10.1016/j.cub.2005.11.064

Homsy JG, Jasper H, Peralta XG, Wu H, Kiehart DP, & Bohmann D. (2005). JNK signaling coordinates integrin and actin functions during Drosophila embryogenesis. Dev Dyn, 235(2), 427–34. https://doi.org/10.1002/dvdy.20649

Todi SV, Franke JD, Kiehart DP, & Eberl DF. (2005). Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila. Curr Biol, 15(9), 862–8. https://doi.org/0.1016/j.cub.2005.03.050

Franke JD, Dong F, Rickoll WL, Kelley MJ, & Kiehart DP. (2005). Rod mutations associated with MYH9-related disorders disrupt nonmuscle myosin-IIA assembly. Blood, 105(1), 161–9. https://doi.org/10.1182/blood-2004-06-2067

Dorman JB, James KE, Fraser SE, Kiehart DP, & Berg CA. (2004). bullwinkle is required for epithelial morphogenesis during Drosophila oogenesis. Dev Biol, 267(2), 320–41. https://doi.org/10.1016/j.ydbio.2003.10.020

Kiehart DP. (2003). Myosins motor Miranda. Mol Cell, 12(6), 1346–7.  https://www.ncbi.nlm.nih.gov/pubmed/14690588

Bayer CA, Halsell SR, Fristrom JW, Kiehart DP, & von Kalm L. (2003). Genetic interactions between the RhoA and Stubble-stubbloid loci suggest a role for a type II transmembrane serine protease in intracellular signaling during Drosophila imaginal disc morphogenesis. Genetics, 165(3), 1417–32. https://www.ncbi.nlm.nih.gov/pubmed/14668391

Hutson MS, Tokutake Y, Chang MS, Bloor JW, Venakides S, Kiehart DP, & Edwards GS. (2003). Forces for morphogenesis investigated with laser microsurgery and quantitative modeling. Science, 300(5616), 145–9. https://doi.org/10.1126/science.1079552

Dutta D, Bloor JW, Ruiz-Gomez M, VijayRaghavan K, & Kiehart DP. (2002). Real-time imaging of morphogenetic movements in Drosophila using Gal4-UAS-driven expression of GFP fused to the actin-binding domain of moesin. Genesis, 34(1–2), 146–51. https://doi.org/10.1002/gene.10113

Kiehart DP, & Franke JD. (2002). Actin dynamics: the arp2/3 complex branches out. Curr Biol, 12(16), R557-9. https://doi.org/10.1016/S0960-9822(02)01053-9

Bloor JW, & Kiehart DP. (2002). Drosophila RhoA regulates the cytoskeleton and cell-cell adhesion in the developing epidermis. Development, 129, 3173–83. https://dev.biologists.org/content/129/13/3173

Ohashi T, Kiehart DP, & Erickson HP. (2002). Dual labeling of the fibronectin matrix and actin cytoskeleton with green fluorescent protein variants. J Cell Sci, 115(Pt 6), 1221–9. https://jcs.biologists.org/content/115/6/1221.long

Bloor JW, & Kiehart DP. (2001). zipper Nonmuscle myosin-II functions downstream of PS2 integrin in Drosophila myogenesis and is necessary for myofibril formation. Dev Biol, 239(2), 215–28. https://doi.org/10.1006/dbio.2001.0452

Crawford JM, Su Z, Varlamova O, Bresnick AR, & Kiehart DP. (2001). Role of myosin-II phosphorylation in V12Cdc42-mediated disruption of Drosophila cellularization. Eur J Cell Biol, 80(3), 240–4. https://doi.org/10.1078/0171-9335-00156

Su Z, & Kiehart DP. (2001). Protein kinase C phosphorylates nonmuscle myosin-II heavy chain from Drosophila but regulation of myosin function by this enzyme is not required for viability in flies. Biochemistry, 40(12), 3606–14. https://doi.org/10.1021/bi010082j

Hallsell SR, Chu BI, & Kiehart DP. (2000). Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during drosophila morphogenesis. Genetics, 155(3), 1253–65. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1461166/

Champagne MB, Edwards KA, Erickson HP, & Kiehart DP. (2000). Drosophila stretchin-MLCK is a novel member of the Titin/Myosin light chain kinase family. J Mol Biol, 300(4), 759–77. https://doi.org/10.1006/jmbi.2000.3802

Halsell SR, Chu BI, & Kiehart DP. (2000). Halsell SR, Chu BI, Kiehart DP. (2000 Jul). Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during Drosophila morphogenesis. Genetics, 155(3), 1253–65. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1461166/

Kiehart DP, Galbraith CG, Edwards KA, Rickoll WL, & Montague RA. (2000). Multiple forces contribute to cell sheet morphogenesis for dorsal closure in Drosophila. J Cell Biol, 149(2), 471–90. https://doi.org/10.1083/jcb.149.2.471

Kiehart DP. (1999). Wound healing: The power of the purse string. Curr Biol, 9(16), R602-5. https://doi.org/10.1016/S0960-9822(99)80384-4

Crawford JM, & Kiehart DP. (1999). Biology in pictures: From one cell to many. Curr Biol, 9(11), R389. https://doi.org/10.1016/S0960-9822(99)80247-4

Ohashi T, Kiehart DP, & Erickson HP. (1999). Dynamics and elasticity of the fibronectin matrix in living cell culture visualized by fibronectin-green fluorescent protein. Proc Natl Acad Sci USA, 96(5), 2153–8. https://doi.org/10.1073/pnas.96.5.2153

Crawford JM, Harden N, Leung T, Lim L, & Kiehart DP. (1998). Cellularization in Drosophila melanogaster is disrupted by the inhibition of rho activity and the activation of Cdc42 function. Dev Biol, 204(1), 151–64. https://doi.org/10.1006/dbio.1998.9061

Aitken PG, Borgdorff AJ, Juta AJ, Kiehart DP, Somjen GG, & Wadman WJ. (1998). Volume changes induced by osmotic stress in freshly isolated rat hippocampal neurons. Pflugers Arch, 436(6), 991–8. https://doi.org/10.1007/s004240050734

Thomas GH, Zarnescu DC, Juedes AE, Bales MA, Londergan A, Korte CC, & Kiehart DP. (1998). Drosophila betaHeavy-spectrin is essential for development and contributes to specific cell fates in the eye. Development, 125(11), 2125–34. https://www.ncbi.nlm.nih.gov/pubmed/9570776

Halsell SR, & Kiehart DP. (1998). Second-site noncomplementation identifies genomic regions required for Drosophila nonmuscle myosin function during morphogenesis. Genetics, 148(4), 1845–63. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1460088/

Thomas GH, Newbern EC, Korte CC, Bales MA, Muse SV, Clark AG, & Kiehart DP. (1997). Intragenic duplication and divergence in the spectrin superfamily of proteins. Mol Biol Evol, 14(12), 1285–95. https://doi.org/10.1093/oxfordjournals.molbev.a025738

Edwards KA, Demsky M, Montague RA, Weymouth N, & Kiehart DP. (1997). GFP-moesin illuminates actin cytoskeleton dynamics in living tissue and demonstrates cell shape changes during morphogenesis in Drosophila. Dev Biol, 191(1), 103–17. https://doi.org/10.1006/dbio.1997.8707

Pederson JD, Kiehart DP, & Mahaffey JW. (1996). The role of HOM-C genes in segmental transformations: reexamination of the Drosophila Sex combs reduced embryonic phenotype. Dev Biol, 180(1), 131–42. https://doi.org/10.1006/dbio.1996.0290

Cooper JA, & Kiehart DP. (1996). Septins may form a ubiquitous family of cytoskeletal filaments, J Cell Biol, 134(6), 1345–8. https://doi.org/10.1083/jcb.134.6.1345

Edwards KA, & Kiehart DP. (1996). Drosophila nonmuscle myosin II has multiple essential roles in imaginal disc and egg chamber morphogenesis. Development, 122(5), 1499–511.  https://www.ncbi.nlm.nih.gov/pubmed/8625837

Mansfield SG, al-Shiwari DY, Ketchum AS, Newbern EC, & Kiehart DP. (1996). Molecular organization and alternative splicing in zipper, the gene that encodes the Drosophila non-muscle myosin II heavy chain. J Mol Biol, 255(1), 98–109. https://doi.org/10.1006/jmbi.1996.0009

Edwards KA, Chang XJ, & Kiehart DP. (1995). Essential light chain of Drosophila nonmuscle myosin II. J Muscle Res Cell Motil, 16(5), 491–8. https://www.ncbi.nlm.nih.gov/pubmed/8567936

Miller KG, & Kiehart DP. (1995). Fly division. J Cell Biol, 131(1), 1–5. https://doi.org/10.1083/jcb.131.1.1

Thomas GH, & Kiehart DP. (1994). Beta heavy-spectrin has a restricted tissue and subcellular distribution during Drosophila embryogenesis. Development, 120(7), 2039–50. https://www.ncbi.nlm.nih.gov/pubmed/7925008

Edwards KA, Montague RA, Shepard S, Edgar BA, Erikson RL, & Kiehart DP. (1994). Identification of Drosophila cytoskeletal proteins by induction of abnormal cell shape in fission yeast. Proc Natl Acad Sci USA, 91(10), 4589–93. https://doi.org/10.1073/pnas.91.10.4589

Kiehart DP, Montague RA, Rickoll WL, Foard D, & Thomas GH. (1994). High-resolution microscopic methods for the analysis of cellular movements in Drosophila embryos. Methods Cell Biol, 44, 507–32. https://www.ncbi.nlm.nih.gov/pubmed/7707969

Young PE, Richman AM, Ketchum AS, & Kiehart DP. (1993). Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function. Genes Dev, 7(1), 29–41. https://doi.org/10.1101/gad.7.1.29

Karess RE, Chang XJ, Edwards KA, Kulkami S, Aguilera I, & Kiehart DP. (1991). The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila. Cell, 65(7), 1177–89. https://doi.org/10.1016/0092-8674(91)90013-o

Young PE, Pesacreta TC, & Kiehart DP. (1991). Dynamic changes in the distribution of cytoplasmic myosin during Drosophila embryogenesis. Development, 111(1), 1–14.  https://www.ncbi.nlm.nih.gov/pubmed/1901784

Rimm DL, Kaiser DA, Bhandari D, Maupin P, Kiehart DP, & Pollard TD. (1990). Identification of functional regions on the tail of Acanthamoeba myosin-II using recombinant fusion proteins. I. High resolution epitope mapping and characterization of monoclonal antibody binding sites. J Cell Biol, 111(6 Pt 1), 2405–16. https://doi.org/10.1083/jcb.111.6.2405

Dubreuil RR, Byers TJ, Stewart CT, & Kiehart DP. (1990). A beta-spectrin isoform from Drosophila (beta H) is similar in size to vertebrate dystrophin. J Cell Biol, 111(5 Pt 1), 1849–58. https://doi.org/10.1083/jcb.111.5.1849

Kiehart DP. (1990). The actin membrane skeleton in Drosophila development. Semin Cell Biol, 1(5), 325–39. https://www.ncbi.nlm.nih.gov/pubmed/2129340

Ketchum AS, Stewart CT, Stewart M, & Kiehart DP. (1990). Complete sequence of the Drosophila nonmuscle myosin heavy-chain transcript: conserved sequences in the myosin tail and differential splicing in the 5’ untranslated sequence. Proc Natl Acad Sci USA, 87(16), 6316–20. https://doi.org/10.1073/pnas.87.16.6316

Kiehart DP. (1990). Molecular genetic dissection of myosin heavy chain function. Cell, 60(3), 347–50. https://doi.org/10.1016/0092-8674(90)90583-Z

Kiehart DP, Ketchum A, Young P, Lutz D, Alfenito MR, Chang XJ, … Stewart CT. (1990). Contractile proteins in Drosophila development. Ann N Y Acad Sci, 522, 233–51. https://doi.org/j.1749-6632.1990.tb21683.x

Pesacreta TC, Byers TJ, Dubreuil R, Kiehart DP, & Branton D. (1989). Drosophila spectrin: the membrane skeleton during embryogenesis. J Cell Biol, 108(5), 1697–1709. https://doi.org/10.1083/jcb.108.5.1697

Kiehart DP, Lutz MS, Chan D, Ketchum AS, Laymon RA, Nguyen B, & Goldstein LS. (1989). Identification of the gene for fly non-muscle myosin heavy chain: Drosophila myosin heavy chains are encoded by a gene family. EMBO J, 8(3), 913–22. https://doi.org/10.1002/j.1460-2075.1989.tb03452.x

Dubreuil R, Byers TJ, Branton D, Kiehart DP, & Goldstein LS. (1987). Drosophilia spectrin. I. Characterization of the purified protein. J Cell Biol, 105(5), 2095–102. https://doi.org/10.1083/jcb.105.5.2095

Byers TJ, Dubreuil R, Branton D, Kiehart DP, & Goldstein LS. (1987). Drosophila spectrin. II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins. J Cell Biol, 105(5), 2103–10. https://doi.org/10.1083/jcb.105.5.2103

Hagen SJ, Kiehart DP, Kaiser DA, & Pollard TD. (1986). Characterization of monoclonal antibodies to Acanthamoeba myosin-I that cross-react with both myosin-II and low molecular mass nuclear proteins. J Cell Biol, 103(6 Pt 1), 2121–28. https://doi.org/10.1083/jcb.103.6.2121

Kiehart DP, & Feghali R. (1986). Cytoplasmic myosin from Drosophila melanogaster. J Cell Biol, 103(4), 1517–25. https://doi.org/10.1083/jcb.103.4.1517

Kiehart DP, Kaiser DA, & Pollard TD. (1986). Antibody inhibitors of nonmuscle myosin function and assembly. Methods Enzymol, 134, 423–53. https://doi.org/10.1016/0076-6879(86)34109-0

Wong AJ, Kiehart DP, & Pollard TD. (1985). Myosin from human erythrocytes. J Biol Chem, 260(1), 46–9. http://www.jbc.org/content/260/1/46.abstract

Eisen A, Kiehart DP, Wieland SJ, & Reynolds GT. (1984). Temporal sequence and spatial distribution of early events of fertilization in single sea urchin eggs. J Cell Biol, 99(5), 1647–54. http://jcb.rupress.org/content/99/5/1647

Kiehart DP, & Pollard TD. (1984). Inhibition of acanthamoeba actomyosin-II ATPase activity and mechanochemical function by specific monoclonal antibodies. J Cell Biol, 99(3), 1024–33. https://doi.org/10.1083/jcb.99.3.1024

Kiehart DP, Kaiser DA, & Pollard TD. (1984). Direct localization of monoclonal antibody-binding sites on Acanthamoeba myosin-II and inhibition of filament formation by antibodies that bind to specific sites on the myosin-II tail. J Cell Biol, 99(3), 1015–23. https://doi.org/10.1083/jcb.99.3.1015

Kiehart DP, Kaiser DA, & Pollard TD. (1984). Monoclonal antibodies demonstrate limited structural homology between myosin isozymes from Acanthamoeba. J Cell Biol, 99(3), 1002–14. https://doi.org/10.1083/jcb.99.3.1002

Kiehart DP, & Pollard TD. (1984). Stimulation of Acanthamoeba actomyosin ATPase activity by myosin-II polymerization. Nature, 308(5692), 864–66. https://doi.org/10.1038/308864a0

Pollard TD, Aebi U, Cooper JA, Fowler WE, Kiehart DP, Smith PR, & Tseng PC. (1982). Actin and myosin function in acanthamoeba. Philos Trans R Soc Lond B Biol Sci, 299(1095), 237–45. https://doi.org/10.1098/rstb.1982.0129

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